Staniol, I was hoping for positive responses to your question. I too have been unable to run JF/A-18 on Win 10. It ran very well on Win 7. Googling for solutions did not produce any specific ways to succeed in running it on Win 10. I am surprised that there are not more reports one way or another about this, since Windows 10 has a high adoption rate, and the sim was popular.
Either no one who has Windows 10 also wants to fly F/A-18, or has given up trying. Or perhaps those with Win 10 maintain Win 7 or earlier for the sim?
Eugene