I have de-winged He-111, Ju-87 and blown up many 109's with a Spit or a Hurri but I've never seen catastropic damage caused by the 109's armament. If you dont' count fire that is. The fire is ineffective though, it always goes out and the plane never blows up!
I constantly take off control surfaces (rudder, elevators) with the 109 cannons, that's usually seen as pretty catastrophical by the ones piloting the planes... I don't expect the cannons to break wing main spars, if that is what you mean, and I don't think that happened a lot in reality.
